Johansson's first leading role was as Amanda, the younger sister of a pregnant teenager who runs away from her foster home in Manny & Lo (1996) alongside Aleksa Palladino and her brother, Hunter.
Her performance received positive reviews: one written for the San Francisco Chronicle noted, "[the film] grows on you, largely because of the charm of ...
Other films during this period include the mystery thriller The Prestige (2006) and the comedy-drama Vicky Cristina Barcelona (2008).
She is a prominent celebrity brand endorser, and also supports various charities and causes.
She has been married twice, to the Canadian actor Ryan Reynolds from 2008 to 2011 and the French businessman Romain Dauriac (with whom she has a daughter) from 2014 to 2017.
With David Arquette, Johansson appeared in the horror comedy Eight Legged Freaks (2002), about a collection of spiders that are exposed to toxic waste, causing them to grow to gigantic proportions and begin killing and harvesting.
In the former, directed by Sofia Coppola, she plays Charlotte, a listless and lonely young wife, opposite Bill Murray.